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This is a non-core endpoint: only basic statistics are computed.

Explicit viral Sepsis

AB1_SEPSIS_VIRAL_EXPL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B00.7
  • Hospital discharge: ICD-9 0545A
  • Cause of death: ICD-10 B00.7
  • Cause of death: ICD-9 0545A

2 out of 7 registries used, show all original rules.

21

4. Check minimum number of events

None

21

5. Include endpoints

None

21

6. Filter based on genotype QC (FinnGen only)

21

Control definitions (FinnGen only)

Control exclude
AB1_SEPSIS_EXPLICIT, AB1_SEPSIS_IMPLICIT

Extra metadata

First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 21 10 11
Unadjusted period prevalence (%) 0.00 0.00 0.00
Median age at first event (years) 38.56 33.02 43.61

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3048929) Epstein Barr virus Ab [Presence] in Serum
7
8
12.33
4.13
1.3
1.3
—
—
—
0
0
(3020630) Protein [Mass/volume] in Serum or Plasma
7
11
8.88
3.51
1.1
1.5
g/l
68.9
68.4
—
7
11
(3018677) aPTT in Platelet poor plasma by Coagulation assay
8
20
5.77
2.93
2.3
3.0
s
35.6
31.1
—
8
20
(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis
5
6
10.40
2.91
1.4
1.0
g/l
10.0
12.5
—
5
6
(3005719) IgG [Mass/volume] in Serum or Plasma
6
11
7.12
2.75
3.0
2.1
g/l
11.4
10.6
—
6
11
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
5
7
8.89
2.70
1.2
1.0
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
5
7
8.89
2.70
1.8
1.0
u/ml
5392.8
291.0
—
5
7
(3007853) Bacteria identified in Skin by Aerobe culture
7
17
5.61
2.62
1.9
1.5
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
7
19
4.97
2.40
1.6
1.6
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
12
54
3.83
2.36
8.8
5.7
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
5
10
6.16
2.20
1.2
1.7
—
—
—
0
0
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
5
12
5.09
1.94
3.8
8.1
u/l
270.4
237.0
—
5
12
(3015736) pH of Urine
13
68
3.37
1.84
6.5
2.8
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
13
72
3.10
1.77
9.8
5.7
mmol/l
1.2
1.2
0.35
13
61
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
7
28
3.23
1.62
2.0
1.5
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
12
66
2.89
1.56
3.4
2.5
ug/l
240.3
90.6
0.39
12
60
(40758558) Short blood count panel - Blood
9
44
2.81
1.52
4.3
5.2
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
9
44
2.81
1.52
5.2
6.5
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
5
17
3.52
1.45
2.4
1.5
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
8
36
2.96
1.44
8.5
3.1
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
10
51
2.83
1.40
1.9
1.5
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
5
19
3.12
1.29
1.4
1.5
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
9
46
2.66
1.26
4.7
4.2
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
5
20
2.95
1.22
7.8
6.2
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
5
20
2.95
1.22
1.4
1.5
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
6
27
2.70
1.03
3.7
1.7
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
6
28
2.59
1.01
2.3
1.7
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
7
38
2.25
0.85
2.0
2.0
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
7
43
1.94
0.76
1.4
1.3
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
8
48
2.07
0.75
3.5
3.5
%
111.8
94.8
—
8
48
(3042936) Bacteria identified in Isolate by Culture
5
27
2.11
0.74
2.4
1.8
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
10
65
2.03
0.72
9.7
3.2
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
11
75
1.98
0.69
3.4
4.3
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
15
176
0.48
0.66
3.3
3.5
mmol/l
1.1
1.3
0.21
15
165
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
10
67
1.94
0.65
2.3
2.7
nmol/l
69.2
78.3
—
10
57
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
16
131
1.92
0.61
7.2
3.7
pmol/l
14.8
15.0
0.11
16
118
(3013826) Glucose [Moles/volume] in Serum or Plasma
13
100
1.78
0.59
9.5
3.4
mmol/l
6.4
6.2
0.15
13
91
(3026008) Bacteria identified in Urine by Culture
7
47
1.73
0.55
4.1
2.0
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
9
65
1.67
0.49
9.9
2.0
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
5
30
1.87
0.48
1.4
1.4
—
945.5
—
0
11
(3026782) Osmolality of Urine
5
32
1.73
0.46
6.2
2.0
mosm/kgh2o
558.8
591.1
—
5
27
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
5
33
1.67
0.45
2.2
2.1
mmol/l
2.4
2.4
—
5
27
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
5
33
1.67
0.45
2.2
1.5
pmol/l
275.2
487.8
—
5
28
(3020564) Creatinine [Moles/volume] in Serum or Plasma
21
195
+∞
0.43
26.8
13.2
umol/l
76.7
75.0
0.09
21
195
(3021960) Folate [Moles/volume] in Serum or Plasma
5
37
1.46
0.26
1.2
1.5
nmol/l
23.8
21.5
—
5
30
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
5
39
1.37
0.25
2.2
1.7
—
—
—
0
0
(3013512) EKG study
5
41
1.29
0.24
23.6
3.8
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
11
128
0.70
0.23
4.4
3.1
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
6
50
1.28
0.22
1.7
3.0
—
—
—
0
0
(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay
0
10
0.00
0.22
0.0
1.2
—
2.0
—
0
5
(3044889) 12 lead EKG panel
14
125
1.36
0.19
9.5
2.9
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
6
53
1.18
0.10
7.0
2.1
e6/l
0.4
0.2
—
6
35
(40768804) Tissue Pathology biopsy report
6
72
0.77
0.09
3.5
1.8
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
14
133
1.16
0.09
13.6
6.9
u/l
85.0
72.7
0.72
14
128
(3037467) Urinalysis macro (dipstick) panel - Urine
13
122
1.17
0.09
6.3
3.4
—
—
—
0
0
(40768800) Prostate Pathology biopsy report
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
0
5
0.00
0.00
0.0
4.4
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
7
70
1.00
0.00
4.3
4.7
ug/l
2.3
2.0
—
7
61
(36304419) Bacteria [Presence] in Urine
5
51
0.97
0.00
7.6
1.9
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3022313) Gas panel - Capillary blood
0
7
0.00
0.00
0.0
4.1
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation
0
8
0.00
0.00
0.0
2.6
—
216.9
—
0
8
(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay
0
7
0.00
0.00
0.0
1.3
—
96.7
—
0
7
(4306422)
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
5
48
1.05
0.00
8.2
2.9
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(4268621)
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
3.3
—
14.8
—
0
6

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: AB1_SEPSIS_VIRAL_EXPL – Explicit viral Sepsis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).