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Plasmodium falciparum malaria

EFO Endpoint Browser PheWeb

AB1_MALARIA_FALCIPARIUM

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — B50
  • Hospital discharge: ICD-9 — 084[0]
  • Hospital discharge: ICD-8 — 084[0]
  • Cause of death: ICD-10 — B50
  • Cause of death: ICD-9 — 084[0]
  • Cause of death: ICD-8 — 084[0]

2 out of 7 registries used, show all original rules.

90

4. Check minimum number of events

None

90

5. Include endpoints

None

90

6. Filter based on genotype QC (FinnGen only)

90

Control definitions (FinnGen only)

Control exclude
AB1_PROTOZOAL

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF5

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1046 394 612
Only index persons 895 341 554
Unadjusted period prevalence (%)
Whole population 0.02 0.01 0.02
Only index persons 0.02 0.01 0.02
Median age at first event (years)
Whole population 38.27 38.30 38.54
Only index persons 37.53 36.68 38.05

-FinnGen-

Key figures

All Female Male
Number of individuals 90 48 42
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 37.50 34.14 41.35

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
81
Matched controls
808
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B50.9
ICD-10 Finland
Plasmodium falciparum malaria, unspecified
+∞
62.9
52
*
0840A
ICD-9 Finland
Malaria, Falciparum malaria [malignant tertian]
+∞
15.1
14
*
B50.0
ICD-10 Finland
Plasmodium falciparum malaria with cerebral complications
+∞
7.4
7
*
08400
ICD-8 Finland
Falicparum malaria (malignant tertian)
+∞
6.3
6
*
B54
ICD-10 Finland
Unspecified malaria
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3018095) Leukocytes [#/volume] in Urine
40
250
2.08
2.85
3.1
3.3
e6/l
13.8
73.0
1.64
27
180
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
8
183
0.38
2.13
2.0
2.9
ng/l
752.8
1084.1
—
8
149
(42870588) Differential panel, method unspecified - Blood
35
229
1.86
2.06
5.7
5.4
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
44
315
1.78
1.90
8.7
9.5
e9/l
0.0
0.0
0.52
34
253
(3021879) Hepatitis B virus core Ab [Presence] in Serum
12
53
2.46
1.90
1.8
1.8
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
25
150
1.92
1.89
2.2
1.8
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
6
19
3.31
1.69
2.5
1.6
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
6
19
3.31
1.69
1.5
1.3
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
16
87
2.02
1.58
1.6
1.7
—
—
—
0
0
(40758558) Short blood count panel - Blood
28
187
1.72
1.48
7.9
6.6
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
17
97
1.93
1.47
2.1
1.8
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
10
46
2.32
1.46
1.7
1.6
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
7
29
2.53
1.42
1.0
1.1
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
14
76
2.00
1.39
1.8
1.7
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
33
237
1.62
1.32
3.3
2.9
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
46
361
1.56
1.25
6.8
6.1
e9/l
0.6
0.6
0.01
36
315
(3037467) Urinalysis macro (dipstick) panel - Urine
57
470
1.58
1.24
3.8
3.8
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
15
87
1.87
1.24
2.3
1.7
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
46
362
1.55
1.23
6.9
6.1
e9/l
0.0
0.0
0.13
36
316
(3013115) Eosinophils [#/volume] in Blood
47
372
1.55
1.22
7.9
6.6
e9/l
0.2
0.2
1.74
38
332
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
8
38
2.21
1.22
1.6
1.5
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
31
223
1.60
1.22
2.9
2.8
e6/l
16.6
43.0
1.23
26
174
(3044889) 12 lead EKG panel
59
493
1.57
1.19
2.9
3.5
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
11
58
2.02
1.18
1.0
1.2
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
46
365
1.53
1.17
6.9
6.2
e9/l
1.9
1.9
0.27
37
325
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
14
82
1.84
1.13
1.8
1.8
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
15
92
1.76
1.05
1.4
1.6
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
54
452
1.49
1.01
3.6
3.9
—
6924.9
—
0
8
(3009542) Hematocrit [Volume Fraction] of Blood
76
685
1.70
1.01
14.9
12.7
%
40.8
40.5
0.26
57
535
(3003694) ABO and Rh group [Type] in Blood
26
189
1.53
0.96
1.5
1.5
—
—
—
0
0
(3023323) Follitropin [Units/volume] in Serum or Plasma
8
44
1.90
0.88
1.4
1.3
iu/l
22.2
22.6
—
8
37
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
75
684
1.58
0.82
14.0
11.7
ml/min/173m2
83.9
84.5
0.07
62
547
(3048689) Calprotectin [Mass/mass] in Stool
13
83
1.66
0.80
3.8
2.7
ug/g
147.4
114.3
—
8
69
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
5
23
2.24
0.77
1.4
2.7
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
50
427
1.38
0.76
10.8
9.8
e9/l
3.9
4.1
0.20
41
374
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
5
24
2.14
0.76
3.8
2.2
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
26
199
1.43
0.74
3.0
2.8
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
18
128
1.51
0.73
2.7
2.6
ng/l
48.3
61.8
0.16
13
90
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
17
120
1.51
0.71
1.6
1.6
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
74
683
1.47
0.65
4.8
4.5
mu/l
1.9
1.9
0.03
66
625
(3045414) Leukocytes [Presence] in Urine
5
30
1.70
0.62
1.6
1.5
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
13
89
1.54
0.62
1.3
1.3
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
0
20
0.00
0.61
0.0
1.3
—
—
—
0
0
(3015171) Extractable nuclear Ab [Units/volume] in Serum
0
21
0.00
0.61
0.0
1.3
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
58
518
1.34
0.60
3.2
3.3
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
61
549
1.34
0.60
4.4
4.0
pmol/l
14.1
14.7
1.09
52
505
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
0
22
0.00
0.60
0.0
1.5
—
56.5
—
0
22
(3004716) Salmonella sp identified in Stool by Organism specific culture
6
37
1.66
0.57
2.0
1.2
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
12
165
0.69
0.52
7.2
6.0
—
—
—
0
0
(3000492) Spirometry study
10
67
1.55
0.52
1.7
1.3
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
5
83
0.58
0.48
1.0
1.3
—
—
—
0
0
(3017732) Neutrophils [#/volume] in Blood
7
48
1.50
0.48
1.3
2.6
e9/l
3.6
3.5
—
7
38
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
6
95
0.61
0.45
1.8
1.3
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
5
32
1.59
0.43
2.0
1.1
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
5
32
1.59
0.43
3.8
2.7
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
61
562
1.27
0.42
8.4
7.5
u/l
73.0
73.8
0.07
54
528
(1002224) Polysomnography panel
5
33
1.54
0.42
1.0
1.1
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
0
16
0.00
0.41
0.0
1.8
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
17
0.00
0.41
0.0
1.7
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
(40768443) Skin Pathology biopsy report
5
34
1.50
0.41
1.6
1.1
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
5
35
1.45
0.40
1.2
1.1
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
36
316
1.23
0.38
3.4
6.8
mmol/l
1.2
1.2
1.14
31
272
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
5
78
0.62
0.37
1.4
7.7
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
6
42
1.46
0.36
1.2
1.2
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
22
184
1.26
0.35
2.4
2.4
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
32
281
1.22
0.33
2.5
1.9
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
42
379
1.20
0.33
7.0
6.6
umol/l
10.9
10.2
0.32
37
361
(3044640) Blood type and Crossmatch panel - Blood
20
236
0.80
0.32
3.0
2.2
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
81
781
1.37
0.29
15.6
14.7
umol/l
76.8
77.2
0.05
81
781
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
29
256
1.20
0.28
1.9
1.8
pmol/l
98.3
97.4
0.04
19
130
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
73
699
1.23
0.27
3.9
3.6
mmol/l
1.2
1.3
0.36
66
647
(40761511) CBC panel - Blood by Automated count
76
786
0.79
0.27
12.2
11.4
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
22
190
1.21
0.26
4.2
4.4
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
24
271
0.84
0.24
2.9
3.7
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
5
40
1.26
0.23
1.0
1.1
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
82
800
1.28
0.22
11.0
9.6
u/l
24.5
27.0
0.86
77
775
(3019060) Gas panel - Arterial blood
5
41
1.23
0.22
1.2
5.1
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
5
41
1.23
0.22
1.4
1.4
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(42870365) C reactive protein [Mass/volume] in Blood by High sensitivity method
0
11
0.00
0.21
0.0
2.2
—
11.8
—
0
5
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
0
10
0.00
0.21
0.0
1.5
—
62.0
—
0
10
(3024928) Oxygen saturation in Venous blood
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(4062490)
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum
0
10
0.00
0.21
0.0
1.4
—
267.8
—
0
5
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
2.9
—
2.7
—
0
13
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
13
0.00
0.21
0.0
2.2
—
13.5
—
0
13
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
57
541
1.15
0.20
2.6
2.7
u/l
47.6
44.0
0.10
50
504
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
27
298
0.87
0.20
4.6
2.5
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
6
50
1.21
0.20
2.0
2.5
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
7
62
1.14
0.18
3.3
3.5
—
—
—
0
0
(3012544) pH of Venous blood
7
62
1.14
0.18
1.3
3.6
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
37
346
1.12
0.15
2.7
3.6
estimate
0.0
0.0
—
6
69
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
76
741
1.16
0.14
13.5
13.2
mg/l
22.5
22.9
0.04
57
580
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
13
113
1.18
0.14
3.4
2.6
e6/l
0.4
0.8
—
8
64
(3021601) Nitrite [Presence] in Urine by Test strip
37
350
1.10
0.12
4.0
4.9
estimate
0.0
0.0
—
6
71
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
18
164
1.12
0.10
2.4
1.8
mg/l
3.3
3.0
0.11
13
142
(3022621) pH of Urine by Test strip
5
44
1.14
0.10
2.0
2.7
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
18
165
1.11
0.09
2.7
3.7
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
15
136
1.12
0.09
1.7
1.3
g/l
2.0
2.4
—
8
85
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
5
60
0.82
0.08
1.2
1.3
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
5
62
0.80
0.08
1.4
3.5
mmol/l
1.8
2.1
—
5
48
(3000963) Hemoglobin [Mass/volume] in Blood
83
832
0.97
0.08
21.2
18.9
g/l
134.4
136.9
0.87
83
817
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
6
74
0.80
0.08
1.3
1.8
—
—
—
0
0
(3022145) Colonoscopy Study observation
7
84
0.82
0.07
1.6
1.3
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
9
83
1.09
0.07
1.8
1.2
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
20
187
1.09
0.07
4.1
4.8
%
17.2
20.4
—
9
90
(3029937) Albumin [Presence] in Urine by Test strip
18
193
0.92
0.07
2.7
3.8
estimate
0.0
0.0
—
6
66
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
74
728
1.09
0.06
4.6
4.0
mmol/l
4.6
4.7
0.29
69
681
(3041096) Erythrocytes [Presence] in Urine by Automated
21
198
1.08
0.06
2.4
3.1
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
32
333
0.94
0.06
4.9
4.3
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
37
357
1.06
0.06
2.8
3.6
estimate
0.0
0.0
—
5
66
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
70
711
0.93
0.05
5.0
4.1
mmol/l
6.2
5.8
0.59
62
654
(3013707) Erythrocyte sedimentation rate by Westergren method
55
538
1.06
0.05
3.4
3.8
mm/h
10.5
10.9
0.10
50
505
(3032080) INR in Blood by Coagulation assay
27
260
1.05
0.04
7.5
7.0
inr
1.2
1.2
—
8
81
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
68
671
1.05
0.03
6.7
5.0
mmol/mol
38.4
39.3
0.36
63
633
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
16
152
1.06
0.02
1.6
1.5
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
18
172
1.06
0.02
4.5
3.1
mg/l
13.0
410.8
0.58
13
115
(3002256) Pathology report gross observation
10
93
1.08
0.02
1.5
1.3
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
11
104
1.07
0.01
1.4
1.9
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
14
134
1.05
0.00
1.4
1.4
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
73
724
1.04
0.00
4.5
3.9
mmol/l
1.4
1.5
0.25
66
672
(3013512) EKG study
18
186
0.96
0.00
4.5
3.5
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
18
178
1.01
0.00
6.1
3.8
mg/mmol
2.4
12.6
—
10
117
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
17
173
0.98
0.00
2.6
2.1
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
26
264
0.98
0.00
3.4
3.7
ng/l
103.5
41.6
0.32
15
169
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
5.0
—
0.6
—
0
6
(3023419) Bacteria identified in Sputum by Culture
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
0
6
0.00
0.00
0.0
1.3
—
91.0
—
0
6
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
2.1
—
—
—
0
0
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3024474) Albumin [Mass/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
263.3
—
0
6
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(4027681)
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(21494890) Protein electrophoresis panel - 24 hour Urine
0
6
0.00
0.00
0.0
6.2
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.0
—
3.1
—
0
6
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3011648) Oxygen content in Venous blood
0
6
0.00
0.00
0.0
1.7
—
11.6
—
0
6
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
12.9
—
0
6
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
5
50
1.00
0.00
1.0
2.6
ug/l
2.4
6.1
—
5
45
(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
7.6
—
62.9
—
0
5
(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
(4035726)
5
55
0.90
0.00
1.2
1.3
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3017817) Protein [Mass] in Urine collected for unspecified duration
0
5
0.00
0.00
0.0
9.2
—
—
—
0
0
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
0
5
0.00
0.00
0.0
1.2
—
253.0
—
0
5
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum
0
5
0.00
0.00
0.0
1.4
—
13.4
—
0
5
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019225) pH of Specimen
5
53
0.94
0.00
4.0
5.3
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3012441) Differential panel - Pleural fluid
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
5
49
1.02
0.00
1.2
1.7
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
(3037692) Legionella sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3024731) MCV [Entitic volume]
83
830
1.00
0.00
20.9
18.8
fl
90.3
90.9
0.50
83
817
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
10
100
1.00
0.00
2.5
2.1
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3035941) MCH [Entitic mass]
83
831
0.98
0.00
20.9
18.8
pg
30.1
30.3
0.45
83
818
(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
63.9
—
0
5
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
124.2
—
0
5
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
7
0.00
0.00
0.0
3.4
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
9
89
1.01
0.00
1.6
1.6
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
6
69
0.86
0.00
1.3
1.7
—
—
—
0
0
(3016038) Potassium [Moles/volume] in Urine
0
5
0.00
0.00
0.0
1.0
—
42.6
—
0
5
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3044242) Glucose [Moles/volume] in Arterial blood
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_MALARIA_FALCIPARIUM and mortality.

Females

Parameter HR [95% CI] p-value
AB1_MALARIA_FALCIPARIUM 2.699 [1.72, 4.25] < 0.001
Birth year 0.99 [0.98, 1.0] 0.021

During the follow-up period (1.1.1998 — 31.12.2019), 58 out of 275 females with AB1_MALARIA_FALCIPARIUM died.

Males

Parameter HR [95% CI] p-value
AB1_MALARIA_FALCIPARIUM 1.672 [1.18, 2.38] 0.004
Birth year 0.989 [0.98, 1.0] 0.023

During the follow-up period (1.1.1998 — 31.12.2019), 54 out of 432 males with AB1_MALARIA_FALCIPARIUM died.

Mortality risk

Mortality risk for people of age

years, who have AB1_MALARIA_FALCIPARIUM.

N-year risk Females Males
1 0.279% 0.374%
5 1.305% 2.311%
10 3.095% 5.381%
15 5.829% 10.142%
20 10.234% 16.771%

Relationships between endpoints

↥

Index endpoint: AB1_MALARIA_FALCIPARIUM – Plasmodium falciparum malaria

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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