This is a non-core endpoint: only basic statistics are computed.
Histoplasmosis
AB1_HISTOPLASMOSIS
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
20 |
4. Check minimum number of eventsNone |
20 |
5. Include endpointsNone |
20 |
6. Filter based on genotype QC (FinnGen only) |
20 |
Control definitions (FinnGen only)
- Control exclude
- AB1_MYCOSES
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Histoplasmosis
based on the number of shared cases.
Similar with more cases:
- Mycoses
- Certain infectious and parasitic diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥FinnGen case counts by registry codes:
Not enough data for upset plot.
Not enough data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 274 | 155 | 119 |
| Only index persons | 225 | 128 | 97 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | - | 29.96 | 14.87 |
| Only index persons | 19.98 | 26.48 | 11.40 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 20 | 14 | 6 |
| Unadjusted period prevalence (%) | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | 39.44 | 30.91 | 59.37 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3013512) EKG study
10
44
3.55
1.91
3.7
3.1
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
10
44
3.55
1.91
7.8
2.0
mg/l
2.9
2.5
—
10
39
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
14
80
3.48
1.80
3.7
4.3
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
5
14
4.38
1.73
2.8
4.1
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
5
15
4.07
1.63
1.2
1.6
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
9
44
2.88
1.53
2.6
2.7
—
—
—
0
0
(3002256) Pathology report gross observation
5
18
3.34
1.37
1.8
1.2
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
8
39
2.74
1.35
2.6
2.3
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
20
171
+∞
1.08
18.4
13.7
umol/l
72.3
71.1
0.10
20
171
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
9
55
2.15
0.91
3.2
3.3
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
10
62
2.23
0.85
2.4
2.7
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
5
23
2.55
0.83
2.2
5.4
%
38.0
31.4
—
5
18
(3003694) ABO and Rh group [Type] in Blood
8
52
1.89
0.71
1.4
1.8
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
9
61
1.86
0.68
12.6
6.8
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
0
20
0.00
0.64
0.0
1.2
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
20
181
+∞
0.64
12.6
10.2
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
6
37
1.88
0.62
1.0
1.7
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
6
38
1.82
0.61
2.5
3.1
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
7
47
1.75
0.56
4.4
3.9
u/l
35.0
28.2
—
7
42
(3023368) Bacteria identified in Blood by Culture
5
33
1.68
0.45
9.4
4.9
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
8
64
1.41
0.33
5.0
2.2
—
—
—
0
0
(3044889) 12 lead EKG panel
12
98
1.56
0.32
2.9
3.1
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
5
39
1.37
0.25
2.6
1.4
nmol/l
17.9
23.4
—
5
31
(1761868) Lipid panel - Serum or Plasma
6
50
1.28
0.22
2.2
2.9
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
11
0.00
0.22
0.0
1.5
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
11
0.00
0.22
0.0
1.5
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
11
0.00
0.22
0.0
1.5
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
11
0.00
0.22
0.0
1.5
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
11
0.00
0.22
0.0
1.5
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
10
0.00
0.22
0.0
1.5
—
—
—
0
0
(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence
0
10
0.00
0.22
0.0
1.5
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
10
0.00
0.22
0.0
1.5
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
12
0.00
0.22
0.0
1.7
—
—
—
0
0
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
0
12
0.00
0.22
0.0
3.6
—
1.2
—
0
12
(3014576) Chloride [Moles/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
11.0
—
104.2
—
0
13
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
8
66
1.35
0.21
4.1
2.6
nmol/l
99.9
76.7
—
8
56
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
0
14
0.00
0.21
0.0
14.9
—
25.4
—
0
14
(3025941) Bacteria identified in Stool by Culture
0
14
0.00
0.21
0.0
1.3
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
10
85
1.35
0.17
12.5
8.0
umol/l
10.1
9.7
—
10
79
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
15
154
0.90
0.10
2.5
4.1
mmol/l
1.2
1.5
4.13
15
146
(3002385) Erythrocyte distribution width [Ratio]
14
147
0.84
0.10
18.3
16.1
%
13.9
13.3
0.88
14
142
(3018095) Leukocytes [#/volume] in Urine
5
61
0.76
0.10
2.8
4.0
e6/l
18.9
37.0
—
5
43
(3006315) Basophils [#/volume] in Blood
9
84
1.13
0.09
17.7
6.6
e9/l
0.0
0.0
—
9
74
(3037467) Urinalysis macro (dipstick) panel - Urine
12
113
1.15
0.09
5.2
4.6
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
9
85
1.11
0.09
17.8
6.6
e9/l
0.6
0.5
—
9
75
(3021589) Normoblasts [#/volume] in Blood
7
76
0.88
0.00
26.6
8.2
e9/l
0.0
0.0
—
7
59
(3045414) Leukocytes [Presence] in Urine
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3020961) Endomysium IgA Ab [Titer] in Serum
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3007461) Platelets [#/volume] in Blood
20
191
+∞
0.00
26.4
18.6
e9/l
248.6
250.4
0.03
20
185
(3023511) Choriogonadotropin [Units/volume] in Urine
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
6
60
1.00
0.00
2.8
3.4
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
0
6
0.00
0.00
0.0
19.3
—
96.7
—
0
6
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010813) Leukocytes [#/volume] in Blood
20
192
+∞
0.00
26.5
18.5
e9/l
6.7
6.5
0.18
20
187
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
33.5
—
0
6
(3026361) Erythrocytes [#/volume] in Blood
20
192
+∞
0.00
26.4
18.5
e12/l
4.4
4.5
0.09
20
187
(3023410) Appearance of Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
0
6
0.00
0.00
0.0
6.5
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
0
5
0.00
0.00
0.0
22.8
—
0.8
—
0
5
(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
4.1
—
24.3
—
0
8
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
0
5
0.00
0.00
0.0
22.8
—
0.7
—
0
5
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3027801) Oxygen [Partial pressure] in Arterial blood
0
6
0.00
0.00
0.0
19.5
—
12.1
—
0
6
(40758558) Short blood count panel - Blood
5
51
0.97
0.00
22.6
6.8
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
8
82
0.96
0.00
6.4
2.9
ug/l
39.0
71.6
—
8
73
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
3.0
—
14.0
—
0
8
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
5
51
0.97
0.00
2.4
2.8
—
—
—
0
0
(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis
0
5
0.00
0.00
0.0
1.0
—
6.2
—
0
5
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
14
139
1.02
0.00
3.7
3.7
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
5
47
1.08
0.00
2.6
3.2
e6/l
0.2
0.0
—
5
32
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
9
87
1.06
0.00
22.9
6.6
e9/l
1.9
1.8
—
9
78
(40768793) Breast Pathology biopsy report
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3015736) pH of Urine
6
64
0.91
0.00
2.8
2.8
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
0
6
0.00
0.00
0.0
19.7
—
5.4
—
0
6
(3001019) Free T4 and TSH panel - Serum or Plasma
0
7
0.00
0.00
0.0
3.7
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation
0
5
0.00
0.00
0.0
1.8
—
239.2
—
0
5
(3019473) Protein [Mass/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
383.3
—
0
7
(3014148) Varicella zoster virus Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3039162) Centromere protein B Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
5
49
1.03
0.00
1.2
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_HISTOPLASMOSIS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have AB1_HISTOPLASMOSIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: AB1_HISTOPLASMOSIS – Histoplasmosis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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