No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
159 |
4. Check minimum number of eventsNone |
159 |
5. Include endpointsNone |
159 |
6. Filter based on genotype QC (FinnGen only) |
159 |
Control definitions (FinnGen only)
- Control exclude
- AB1_VIRAL_HEPATITIS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- B15-B19
- Name in latin
- Hepatitis A acuta
Similar endpoints
↥List of similar endpoints to
Acute hepatitis A
based on the number of shared cases.
Similar with more cases:
- Viral hepatitis, IBD co-morbidity
- Viral hepatitis
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1602 | 688 | 896 |
| Only index persons | 1328 | 598 | 730 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.03 |
| Only index persons | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 36.85 | 37.94 | 35.93 |
| Only index persons | 34.38 | 35.37 | 33.56 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 159 | 81 | 78 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | 38.51 | 37.34 | 39.72 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 150
- Matched controls
- 1502
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B15.9
ICD-10 Finland
Hepatitis A without hepatic coma
+∞
111.9
93
*
0701A
ICD-9 Finland
Viral hepatitis A without mention of hepatic coma
+∞
49.8
45
*
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
59.5
21.9
25
5
B18.2
ICD-10 Finland
Chronic viral hepatitis C
+∞
13.7
13
*
0700A
ICD-9 Finland
Viral hepatitis A with hepatic coma
+∞
8.4
8
*
B19.9
ICD-10 Finland
Unspecified viral hepatitis without hepatic coma
+∞
7.3
7
*
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
17.7
6.8
10
6
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.6
6.8
23
57
B15.0
ICD-10 Finland
Hepatitis A with hepatic coma
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
12
20
6.41
7.01
1.0
1.1
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
8
5
16.73
5.47
1.8
1.2
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
99
682
2.20
5.38
7.7
6.4
umol/l
11.3
11.0
0.12
94
647
(3016650) Hepatitis A virus Ab [Presence] in Serum
12
27
4.73
5.13
1.1
1.1
—
—
—
0
0
(3006922) Hepatitis E virus Ab [Presence] in Serum
6
5
12.39
3.79
1.0
1.2
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
18
74
2.62
3.18
3.9
2.4
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
15
58
2.75
2.97
4.4
2.5
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
69
487
1.74
2.87
9.5
7.0
inr
1.1
1.2
0.16
16
151
(3044290) Cell count panel - Cerebral spinal fluid
8
19
4.37
2.71
2.3
1.5
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
90
696
1.68
2.59
7.2
6.2
e9/l
2.1
1.8
0.54
81
625
(3021879) Hepatitis B virus core Ab [Presence] in Serum
24
124
2.10
2.57
1.6
1.6
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
6
11
5.62
2.56
3.8
1.3
—
—
—
0
0
(3005719) IgG [Mass/volume] in Serum or Plasma
21
103
2.20
2.55
2.2
2.4
g/l
11.7
10.2
0.63
21
94
(40758558) Short blood count panel - Blood
51
342
1.72
2.49
9.3
7.8
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
78
589
1.64
2.41
12.5
9.9
e9/l
0.0
0.0
0.50
65
482
(3013115) Eosinophils [#/volume] in Blood
89
696
1.63
2.38
7.5
6.5
e9/l
0.2
0.2
0.48
79
623
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
6
13
4.75
2.29
1.0
1.0
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
30
176
1.87
2.26
2.0
1.8
%
1.6
1.4
0.30
30
158
(3028707) Methadone [Presence] in Urine by Screen method
9
29
3.23
2.26
1.8
1.3
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
86
674
1.60
2.23
7.4
6.3
e9/l
0.0
0.0
0.59
73
590
(3015377) Calcium [Moles/volume] in Serum or Plasma
58
414
1.63
2.20
3.8
3.6
mmol/l
2.4
2.4
0.72
53
361
(3028026) IgM [Mass/volume] in Serum or Plasma
18
89
2.15
2.16
1.2
1.7
g/l
1.1
1.1
0.00
18
80
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
25
142
1.90
2.08
2.5
1.7
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
95
772
1.57
2.04
13.8
10.4
e9/l
3.9
4.2
1.07
83
684
(3001604) Monocytes [#/volume] in Blood
85
674
1.56
2.03
7.5
6.2
e9/l
0.6
0.6
0.09
73
587
(3001122) Ferritin [Mass/volume] in Serum or Plasma
74
569
1.56
2.02
3.0
2.6
ug/l
92.2
107.3
0.41
67
523
(3026782) Osmolality of Urine
38
248
1.70
2.01
3.1
2.7
mosm/kgh2o
532.8
554.3
0.19
33
209
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
25
144
1.87
2.00
2.6
1.8
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
50
0.00
1.92
0.0
2.0
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
30
187
1.74
1.86
1.2
1.4
titre
320.0
413.3
—
6
45
(3024561) Albumin [Mass/volume] in Serum or Plasma
70
540
1.53
1.85
7.1
4.6
g/l
34.9
35.9
0.85
64
514
(3037756) Immunofixation for Serum or Plasma
7
23
3.13
1.82
1.0
2.0
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
113
969
1.57
1.81
4.8
4.3
mm/h
13.1
10.8
0.81
106
899
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
12
55
2.28
1.72
2.2
2.3
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
41
284
1.60
1.72
2.9
2.0
mg/l
3.0
3.2
0.25
36
241
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
6
21
2.93
1.52
1.3
1.4
—
—
—
0
0
(3012544) pH of Venous blood
20
118
1.79
1.50
2.2
3.7
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
9
38
2.45
1.48
1.3
1.2
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
5
16
3.19
1.45
1.0
1.3
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
33
226
1.58
1.44
1.5
1.6
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
23
144
1.70
1.42
3.0
2.0
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
58
452
1.45
1.38
7.4
5.9
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
10
47
2.20
1.37
1.1
1.3
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
12
61
2.05
1.37
1.8
1.2
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
41
0.00
1.33
0.0
1.5
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
9
43
2.16
1.32
14.6
1.5
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
123
1105
1.50
1.32
26.3
17.0
%
13.8
13.7
0.31
123
1091
(3027944) Amphetamines [Presence] in Urine
12
62
2.01
1.31
1.8
1.3
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
12
62
2.01
1.31
1.8
1.2
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
12
62
2.01
1.31
1.8
1.2
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
10
48
2.16
1.30
4.1
2.6
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
8
35
2.35
1.29
1.9
1.2
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
6
26
2.36
1.20
1.0
1.2
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
6
26
2.36
1.20
1.0
1.2
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
32
228
1.51
1.18
1.4
1.2
u/ml
22.2
6.4
—
10
89
(3016879) Cocaine [Presence] in Urine
11
58
1.96
1.15
1.8
1.2
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
8
40
2.05
1.14
1.0
1.2
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
25
170
1.56
1.13
2.0
2.2
%
17.9
22.3
1.39
19
145
(3000494) Fungus identified in Specimen by Culture
24
162
1.57
1.12
1.2
1.3
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
27
188
1.53
1.11
2.3
1.7
—
—
—
0
0
(3000570) Elastase.pancreatic [Mass/mass] in Stool
8
41
2.00
1.10
1.9
1.5
ug/g
263.8
258.2
—
8
21
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
24
163
1.56
1.10
3.0
2.2
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
9
47
1.97
1.04
2.0
1.2
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
100
884
1.35
1.04
4.9
4.3
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
41
315
1.41
1.03
6.7
4.4
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
19
124
1.60
1.02
3.9
3.5
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
29
209
1.47
1.02
2.7
1.9
—
—
—
0
0
(3044889) 12 lead EKG panel
101
897
1.35
1.00
4.4
3.7
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
18
117
1.61
0.99
2.9
1.9
nmol/l
312.8
388.3
1.14
18
108
(3018418) pH of Serum or Plasma
46
365
1.37
0.96
2.9
4.3
ph
7.4
7.4
—
7
74
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
12
70
1.77
0.95
1.6
1.5
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
44
347
1.37
0.95
1.6
1.7
mmol/l
1.6
1.4
0.71
39
288
(3013826) Glucose [Moles/volume] in Serum or Plasma
88
770
1.32
0.94
5.9
4.7
mmol/l
6.7
6.7
0.04
83
709
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
6
27
2.27
0.94
1.3
1.2
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
135
1261
1.47
0.94
4.6
4.4
mmol/l
6.1
5.9
0.67
129
1169
(3005322) IgE [Units/volume] in Serum or Plasma
13
79
1.70
0.91
1.2
1.2
u/ml
111.9
183.8
0.80
13
71
(1761868) Lipid panel - Serum or Plasma
44
541
0.74
0.90
3.3
2.8
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
8
44
1.86
0.87
1.1
2.9
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
6
31
1.97
0.85
1.0
1.2
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
6
33
1.85
0.80
1.7
1.3
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
6
33
1.85
0.80
1.5
1.3
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
25
0.00
0.79
0.0
1.3
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
25
0.00
0.79
0.0
1.8
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
132
1240
1.38
0.77
23.4
14.3
%
40.1
40.7
0.42
106
978
(3018095) Leukocytes [#/volume] in Urine
55
462
1.29
0.77
3.4
3.6
e6/l
25.4
68.9
1.04
37
315
(3002582) Erythrocytes [#/volume] in Urine
48
396
1.30
0.76
2.8
2.9
e6/l
164.3
203.4
0.07
34
291
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
105
957
1.29
0.76
3.8
3.8
pmol/l
14.3
14.7
0.66
96
875
(3007164) IgA [Mass/volume] in Serum or Plasma
37
295
1.33
0.74
1.4
1.4
g/l
2.4
2.4
0.06
24
178
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
139
1320
1.42
0.72
20.2
13.7
mg/l
23.5
21.4
0.27
116
1042
(3038515) Glucose [Moles/volume] in Venous blood
5
26
1.95
0.71
3.0
3.9
mmol/l
6.4
7.9
—
5
26
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
5
26
1.95
0.71
1.0
1.3
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
5
26
1.95
0.71
1.0
1.3
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
43
353
1.30
0.71
2.8
2.7
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
67
583
1.26
0.69
7.6
7.4
mmol/l
1.2
1.2
0.08
60
493
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
47
392
1.28
0.69
2.4
2.1
u/l
148.1
162.5
0.17
40
370
(3030467) Casts [#/volume] in Urine by Automated count
44
364
1.29
0.68
2.8
2.8
e6/l
0.2
0.4
0.61
31
258
(3004588) Protein electrophoresis panel - Serum or Plasma
12
78
1.58
0.67
1.4
3.0
—
—
—
0
0
(3013512) EKG study
29
364
0.75
0.67
4.7
4.0
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
61
529
1.25
0.64
2.5
2.4
nmol/l
81.6
74.5
0.87
55
475
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
28
219
1.34
0.64
2.0
2.5
e6/l
15.2
0.8
0.49
15
118
(3003694) ABO and Rh group [Type] in Blood
44
367
1.28
0.64
1.3
1.4
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
5
30
1.69
0.62
1.0
1.3
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
125
1177
1.29
0.62
4.7
4.6
mu/l
1.8
1.9
0.17
117
1080
(3021440) Promyelocytes/100 leukocytes in Blood
16
114
1.45
0.61
2.8
4.4
%
0.0
0.2
—
5
36
(40768800) Prostate Pathology biopsy report
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
(3019225) pH of Specimen
7
112
0.61
0.60
3.6
5.2
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
0
21
0.00
0.60
0.0
3.7
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
30
240
1.31
0.60
4.0
3.5
ng/l
29.7
216.2
1.64
22
184
(3017181) Myelocytes/100 leukocytes in Blood
17
124
1.42
0.58
2.8
4.3
%
0.4
0.8
—
5
39
(3011397) Hemoglobin [Presence] in Urine by Test strip
35
287
1.28
0.58
2.9
3.6
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
25
196
1.33
0.57
1.8
1.7
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
147
1420
1.47
0.57
14.4
10.6
u/l
30.0
27.2
0.89
142
1380
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
57
500
1.22
0.53
2.2
1.9
pmol/l
104.8
97.0
0.67
34
258
(3021601) Nitrite [Presence] in Urine by Test strip
73
657
1.21
0.52
4.9
5.0
estimate
0.0
0.0
0.00
14
125
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
139
1336
1.32
0.50
4.6
4.8
mmol/l
2.8
2.8
0.05
127
1244
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
128
1219
1.26
0.50
6.1
5.6
mmol/mol
39.7
39.8
0.04
123
1145
(3000991) Gas panel - Venous blood
14
102
1.41
0.49
8.0
9.3
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
10
141
0.69
0.47
1.5
1.7
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
39
333
1.23
0.47
3.4
3.9
estimate
0.0
0.0
0.50
14
121
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
25
204
1.27
0.44
2.2
2.7
e6/l
8.0
2.3
0.42
12
105
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
10
139
0.70
0.44
8.0
7.2
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
131
1257
1.24
0.43
15.0
12.5
ml/min/173m2
86.5
84.3
0.60
115
1037
(3020564) Creatinine [Moles/volume] in Serum or Plasma
144
1397
1.33
0.42
21.1
15.7
umol/l
73.8
77.3
1.26
144
1397
(46235355) HIV 1 and 2 tests - Meaningful Use set
32
271
1.23
0.41
2.3
2.0
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
(42870365) C reactive protein [Mass/volume] in Blood by High sensitivity method
0
17
0.00
0.41
0.0
1.5
—
21.9
—
0
5
(3008757) Leukocyte morphology finding [Identifier] in Blood
0
17
0.00
0.41
0.0
3.8
—
—
—
0
0
(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum
5
34
1.49
0.40
1.8
4.0
—
1.7
—
0
5
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
18
142
1.30
0.40
1.9
1.9
—
—
—
0
0
(3014218) Bicarbonate [Moles/volume] standard in Arterial blood
8
61
1.33
0.40
11.9
12.4
mmol/l
24.6
24.7
—
8
55
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
28
235
1.23
0.39
1.4
1.3
iu/ml
32.9
36.5
—
9
80
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
0
19
0.00
0.39
0.0
2.7
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
136
1314
1.24
0.38
4.1
4.4
mmol/l
4.7
4.7
0.13
124
1231
(21494755) Public health laboratory ask at order entry panel
14
179
0.76
0.38
1.6
1.4
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
32
275
1.20
0.36
1.7
1.8
mg/l
0.6
1.2
1.68
24
220
(3052851) Hemolysis interference index of Serum or Plasma
6
41
1.48
0.36
1.0
3.6
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
51
458
1.17
0.36
2.9
3.0
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
6
42
1.45
0.36
1.2
1.3
—
—
—
0
0
(4034850)
6
43
1.41
0.35
3.7
8.5
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
72
667
1.15
0.33
3.4
3.6
estimate
0.0
0.0
0.00
13
120
(3000850) Epithelial cells [#/volume] in Urine
31
269
1.19
0.32
2.6
2.4
e6/l
4.2
5.8
0.76
26
228
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
35
308
1.17
0.31
1.9
2.2
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
41
366
1.16
0.31
3.6
4.0
mg/mmol
7.2
11.3
0.40
28
233
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
135
1310
1.20
0.31
4.0
4.4
mmol/l
1.4
1.4
0.42
125
1217
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
10
75
1.36
0.31
1.0
1.0
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
7
54
1.31
0.31
3.7
3.8
%
48.1
49.8
—
7
54
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
7
56
1.26
0.30
2.7
2.6
%
3.0
1.5
—
7
56
(3035350) Ketones [Presence] in Urine by Test strip
70
652
1.13
0.29
3.4
3.6
estimate
0.0
0.0
0.00
14
128
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
10
76
1.34
0.29
7.3
7.0
mmol/l
25.0
25.3
—
10
76
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
55
507
1.13
0.26
3.8
3.7
—
—
—
0
0
(1002224) Polysomnography panel
9
72
1.26
0.26
1.2
1.1
—
—
—
0
0
(4035726)
14
114
1.25
0.26
1.4
1.4
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
5
38
1.33
0.23
2.4
1.7
—
—
—
0
0
(3027801) Oxygen [Partial pressure] in Arterial blood
15
125
1.22
0.23
12.1
8.9
kpa
13.5
12.0
0.35
15
120
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
15
125
1.22
0.23
12.1
9.0
kpa
5.3
5.1
0.42
15
119
(3025941) Bacteria identified in Stool by Culture
11
88
1.27
0.23
2.0
1.3
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
5
39
1.29
0.23
2.2
1.2
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
5
39
1.29
0.23
1.0
1.2
—
—
—
0
0
(3020891) Body temperature
5
40
1.26
0.22
2.2
4.8
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
5
41
1.23
0.22
2.4
1.7
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
63
592
1.11
0.21
4.4
4.1
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
10
0.00
0.21
0.0
3.2
—
—
—
0
0
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
12
0.00
0.21
0.0
3.0
—
—
—
0
0
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.5
—
1.1
—
0
12
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
(3011648) Oxygen content in Venous blood
0
13
0.00
0.21
0.0
1.9
—
12.8
—
0
13
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
12
99
1.23
0.20
4.9
1.4
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
45
418
1.11
0.19
2.1
2.2
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
29
263
1.13
0.18
1.8
1.6
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
7
61
1.15
0.18
24.1
10.8
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
9
78
1.16
0.15
2.6
1.8
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
9
78
1.16
0.15
1.1
1.2
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
32
346
0.91
0.15
4.2
4.1
%
26.2
21.5
0.51
17
157
(3012516) Albumin [Mass/volume] in Urine
37
344
1.10
0.15
3.0
3.3
mg/l
1846.2
264.8
0.41
26
217
(4010399)
7
85
0.82
0.15
1.1
1.6
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
10
117
0.84
0.13
17.5
9.2
%
96.6
95.6
—
10
112
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
52
495
1.08
0.12
4.6
3.5
ng/l
26.2
35.6
0.36
33
311
(3041096) Erythrocytes [Presence] in Urine by Automated
40
378
1.08
0.11
3.4
3.3
—
—
—
0
0
(3000492) Spirometry study
16
145
1.12
0.09
1.3
1.5
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
20
184
1.10
0.09
1.2
1.2
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
6
53
1.14
0.09
1.8
1.8
nmol/l
44.0
36.5
—
6
53
(3026008) Bacteria identified in Urine by Culture
36
342
1.07
0.09
3.6
3.0
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
6
57
1.05
0.08
1.7
1.8
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
24
256
0.93
0.08
2.7
2.9
ug/l
0.7
0.8
0.07
15
148
(3000330) Specific gravity of Urine by Test strip
7
65
1.08
0.08
3.4
3.7
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
7
68
1.03
0.08
1.6
1.2
—
—
—
0
0
(3008898) HLA-B27 [Presence]
6
71
0.84
0.08
1.2
1.1
—
—
—
0
0
(3019060) Gas panel - Arterial blood
6
71
0.84
0.08
12.5
4.8
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
7
81
0.86
0.07
2.0
1.3
—
—
—
0
0
(3022621) pH of Urine by Test strip
7
83
0.84
0.07
3.0
2.2
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
10
111
0.89
0.06
5.7
3.5
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
14
151
0.92
0.05
1.6
1.5
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
12
110
1.10
0.05
1.3
1.1
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
34
350
0.96
0.03
2.3
3.0
ng/l
1619.3
868.0
0.46
26
286
(40761511) CBC panel - Blood by Automated count
141
1401
1.06
0.03
19.2
12.2
—
—
—
0
0
(3035941) MCH [Entitic mass]
147
1478
0.93
0.03
28.7
19.8
pg
29.8
30.2
1.53
147
1458
(3024731) MCV [Entitic volume]
147
1478
0.93
0.03
28.6
19.8
fl
89.7
90.7
1.48
147
1458
(3000963) Hemoglobin [Mass/volume] in Blood
147
1478
0.93
0.03
28.8
20.0
g/l
134.3
137.2
1.58
147
1457
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
128
1271
1.04
0.02
3.8
4.0
mmol/l
1.3
1.3
0.10
116
1176
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
32
312
1.03
0.02
1.4
1.2
u/ml
1.6
1.6
—
8
87
(3019832) Treponema pallidum Ab [Presence] in Serum
14
139
1.01
0.00
2.7
1.8
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
14
141
0.99
0.00
1.6
1.5
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
28
279
1.00
0.00
3.6
3.6
kg/l
1.0
1.0
—
5
30
(40768804) Tissue Pathology biopsy report
52
523
0.99
0.00
2.0
2.0
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
92
915
1.01
0.00
3.6
3.4
—
—
—
0
0
(3022145) Colonoscopy Study observation
17
165
1.03
0.00
1.1
1.3
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
18
185
0.97
0.00
1.3
1.4
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
14
135
1.04
0.00
19.9
22.4
—
1.4
—
0
23
(3002256) Pathology report gross observation
16
155
1.04
0.00
1.4
1.2
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
4.2
—
—
—
0
0
(3020650) Glucose [Presence] in Urine
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3006462) Nitrate [Presence] in Urine
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
0.00
0.0
1.0
—
116.5
—
0
6
(3016436) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
5.7
—
223.8
—
0
6
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3047189) Immunofixation for 24 hour Urine
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(40761535) Cells panel - Urine sediment
8
85
0.94
0.00
2.3
4.2
—
—
—
0
0
(3036071) Salmonella sp Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40758292) HTLV I+II Ab panel - Serum
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
30.5
—
0
6
(3037692) Legionella sp identified in Specimen by Organism specific culture
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.3
—
116.9
—
0
9
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
4.2
—
—
—
0
0
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3044242) Glucose [Moles/volume] in Arterial blood
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline
0
8
0.00
0.00
0.0
1.0
—
8.9
—
0
8
(3035947) Staphylolysin Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3017569) Oxygen content in Arterial blood
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(3025018) Bordetella pertussis Ab [Titer] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3009550) Parvovirus B19 IgG Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
5
52
0.96
0.00
2.0
1.3
—
—
—
0
0
(4211845)
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3008152) Bicarbonate [Moles/volume] in Arterial blood
6
66
0.91
0.00
14.3
7.8
mmol/l
25.0
24.6
—
6
61
(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
7
0.00
0.00
0.0
2.6
—
120.7
—
0
7
(40760892) CBC W Ordered Manual Differential panel - Blood
31
310
1.00
0.00
5.6
5.3
—
—
—
0
0
(3028433) Virus identified in Specimen by Culture
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum
0
5
0.00
0.00
0.0
2.0
—
84.9
—
0
5
(3042299) inFLIXimab [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
4.4
—
4.4
—
0
5
(3016244) Insulin [Units/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.9
—
16.0
—
0
7
(40757494) Bilirubin.total [Moles/volume] in Blood
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3002619) Bacteria identified in Specimen by Culture
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
5
56
0.89
0.00
1.4
2.2
—
—
—
0
0
(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(4027681)
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3014271) Vancomycin [Susceptibility]
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3037556) Urate [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_HEPATITIS_A and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_HEPATITIS_A | 2.036 [1.4, 2.96] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.506 |
During the follow-up period (1.1.1998 — 31.12.2019), 51 out of 336 females with AB1_HEPATITIS_A died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_HEPATITIS_A | 3.07 [2.26, 4.18] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 110 out of 473 males with AB1_HEPATITIS_A died.
Mortality risk
Mortality risk for people of age
years, who have AB1_HEPATITIS_A.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.231% | 0.453% |
| 5 | 1.239% | 3.157% |
| 10 | 3.161% | 7.868% |
| 15 | 6.288% | 14.48% |
| 20 | 11.069% | 23.486% |
Relationships between endpoints
↥Index endpoint: AB1_HEPATITIS_A – Acute hepatitis A
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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