info icon

This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Chagas' disease

AB1_CHAGA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B57
  • Hospital discharge: ICD-9 086[0-2]
  • Hospital discharge: ICD-8 08[6]
  • Cause of death: ICD-10 B57
  • Cause of death: ICD-9 086[0-2]
  • Cause of death: ICD-8 08[6]

2 out of 7 registries used, show all original rules.

9

4. Check minimum number of events

None

9

5. Include endpoints

None

9

6. Filter based on genotype QC (FinnGen only)

9

Control definitions (FinnGen only)

Control exclude
AB1_PROTOZOAL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Not enough data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 77 33 43
Only index persons 58 29 29
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 49.85 50.48 49.46
Only index persons 37.25 43.41 31.10

-FinnGen-

Key figures

All Female Male
Number of individuals 9 5 -
Unadjusted period prevalence (%) 0.00 0.00 -
Median age at first event (years) 51.05 55.25 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3044889) 12 lead EKG panel
9
49
+∞
2.02
6.0
4.6
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
0
27
0.00
0.96
0.0
5.5
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
9
75
+∞
0.46
4.4
4.5
mmol/l
5.8
5.7
—
9
66
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
0
10
0.00
0.23
0.0
5.8
—
1.2
—
0
10
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
9
77
+∞
0.22
5.8
4.6
mmol/mol
37.7
39.6
—
9
70
(3001019) Free T4 and TSH panel - Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
0
9
0.00
0.00
0.0
5.8
—
—
—
0
0
(1616796) Gas panel - Central venous blood
0
5
0.00
0.00
0.0
5.8
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
9
0.00
0.00
0.0
2.4
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
56.4
—
0
5
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
9
81
+∞
0.00
5.3
5.4
mmol/l
2.7
2.7
—
9
72
(3002256) Pathology report gross observation
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3013290) Carbon dioxide [Partial pressure] in Blood
0
6
0.00
0.00
0.0
3.2
—
5.2
—
0
6
(3019225) pH of Specimen
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
0
6
0.00
0.00
0.0
3.2
—
8.1
—
0
6
(3010421) pH of Blood
0
6
0.00
0.00
0.0
3.5
—
7.4
—
0
6
(3000492) Spirometry study
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
9
81
+∞
0.00
29.4
13.9
umol/l
110.2
86.7
—
9
81

Mortality – FinRegistry

Association

Association between endpoint AB1_CHAGA and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have AB1_CHAGA.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: AB1_CHAGA – Chagas' disease

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data