This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Pemphigoid
L12_PEMPHIGOID
bullous pemphigoid: Bullous pemphigoid (BP) is the most common form of autoimmune bullous dermatosis.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpoints |
915 |
6. Filter based on genotype QC (FinnGen only) |
915 |
Control definitions (FinnGen only)
- Control exclude
- L12_BULLOUS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L10-L14
- Name in latin
- Pemphigoides
Similar endpoints
↥List of similar endpoints to
Pemphigoid
based on the number of shared cases.
Similar with more cases:
- Bullous disorders
- Autoimmune diseases
- Used for control exclusion in common control thyroid runs
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 915 | 469 | 446 |
| Unadjusted period prevalence (%) | 0.18 | 0.16 | 0.20 |
| Median age at first event (years) | 72.76 | 70.98 | 74.63 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 799
- Matched controls
- 7992
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L12.0
ICD-10 Finland
Bullous pemphigoid
16384.0
323.0
633
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
15.2
208.9
394
479
L12.9
ICD-10 Finland
Pemphigoid, unspecified
+∞
177.9
164
*
D07AD01
ATC
clobetasol; topical
9.9
160.1
387
692
D07AC01
ATC
betamethasone; topical
6.1
121.4
509
1794
H02AB06
ATC
prednisolone; systemic
6.1
115.1
612
2789
L12.8
ICD-10 Finland
Other pemphigoid
+∞
87.1
82
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
5.5
86.3
313
835
E0000UV
ATC
NA
4.3
80.8
481
2090
L12.1
ICD-10 Finland
Cicatricial pemphigoid
+∞
67.7
64
*
L04AX01
ATC
azathioprine; systemic
11.2
63.3
125
130
J04BA02
ATC
dapsone; oral
69.5
61.4
70
11
TQW80
NOMESCO Finland
Local dermatologic skincare
12.5
54.1
100
90
L13.9
ICD-10 Finland
Bullous disorder, unspecified
69.3
50.9
58
9
135
Kela drug reimbursment
Pemphigus
+∞
50.5
48
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.1
49.8
422
2113
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
5.2
46.6
158
359
D07AC13
ATC
mometasone; topical
3.2
46.0
335
1483
L12
ICD-10 Finland
Pemphigoid
127.4
45.3
48
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
4.3
44.3
185
519
ECA20
NOMESCO Finland
Biopsy of gingiva
22.6
35.2
51
24
D07AB08
ATC
desonide; topical
4.1
34.5
148
418
L12.2
ICD-10 Finland
Chronic bullous disease of childhood
+∞
33.6
32
*
D07BC01
ATC
betamethasone and antiseptics; topical
3.6
31.4
162
533
E000001
ATC
NA
2.9
30.9
233
1001
D07AB02
ATC
hydrocortisone butyrate; topical
2.5
27.6
281
1420
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.8
25.5
197
845
XQ848
NOMESCO Finland
Dermatological photography
6.4
24.4
66
111
A02BC02
ATC
pantoprazole; systemic
2.2
24.2
558
4073
L29.9
ICD-10 Finland
Pruritus, unspecified
7.1
23.0
57
85
J01DB01
ATC
cefalexin; oral
2.4
22.7
651
5165
R06AE07
ATC
cetirizine; oral
2.1
21.2
350
2163
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.7
19.9
154
652
D02AX
ATC
Other emollients and protectives
6.5
19.4
51
83
L13.0
ICD-10 Finland
Dermatitis herpetiformis
102.4
18.6
20
*
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
4.9
18.6
62
135
C03CA01
ATC
furosemide; systemic
1.9
16.9
349
2291
H02AB07
ATC
prednisone; oral
2.5
16.9
153
703
EKA10
NOMESCO Finland
Biopsy of cheek
7.0
16.2
40
60
S18
ICPC
Laceration/cut
1.9
16.0
376
2570
S99
ICPC
Skin disease other
6.4
16.0
42
69
L13.8
ICD-10 Finland
Other specified bullous disorders
+∞
15.7
15
*
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
6.2
15.6
42
71
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.9
15.6
103
394
A10BH05
ATC
linagliptin; oral
3.4
15.4
78
248
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
15.2
403
2853
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.0
14.9
89
319
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
14.4
190
1035
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.0
14.4
58
153
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
5.1
14.4
45
92
L30.3
ICD-10 Finland
Infective dermatitis
4.7
14.3
48
106
A46
ICD-10 Finland
Erysipelas
2.2
14.2
156
785
S29
ICPC
Skin symptom/complaint other
2.2
14.1
165
852
L29.8
ICD-10 Finland
Other pruritus
9.1
14.1
29
33
D02AE01
ATC
carbamide; topical
3.3
13.9
73
239
K12.10
ICD-10 Finland
Stomatitis NOS
20.5
13.8
20
10
L12.3
ICD-10 Finland
Acquired epidermolysis bullosa
+∞
13.6
13
*
S97
ICPC
Chronic ulcer skin
3.0
13.5
82
296
J01FF01
ATC
clindamycin; systemic
1.9
13.3
225
1344
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.9
13.0
228
1380
A10AE04
ATC
insulin glargine; parenteral
2.5
12.9
103
441
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
12.8
164
875
A28
ICPC
Limited function/disability NOS
2.0
12.7
183
1025
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
12.3
155
823
L30.0
ICD-10 Finland
Nummular dermatitis
3.9
12.2
50
135
SBA00
NOMESCO Finland
Microbiological examinations
5.4
11.9
35
67
D09AB01
ATC
zinc bandage without supplements; topical
5.0
11.7
37
77
H13.3*L12.9
ICD-10 Finland
Ocular pemphigoid
+∞
11.5
11
*
L10.9
ICD-10 Finland
Pemphigus, unspecified
121.6
11.5
12
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.3
11.3
111
527
SPAT1229
SPAT
Assessment of need for aid
2.3
10.7
102
475
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.6
10.7
83
346
R06AE09
ATC
levocetirizine; oral
2.2
10.6
109
527
R06AX27
ATC
desloratadine; oral
1.9
10.6
171
994
J01AA07
ATC
tetracycline; systemic
2.3
10.5
101
474
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.7
10.4
70
271
L10.0
ICD-10 Finland
Pemphigus vulgaris
111.4
10.4
11
*
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
10.2
247
1639
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.8
10.2
67
256
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
10.1
256
1722
E000003
ATC
NA
3.5
10.1
47
142
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
10.1
233
1524
C07AB07
ATC
bisoprolol; oral
1.6
9.9
422
3267
T90
ICPC
Diabetes non-insulin dependent
1.8
9.9
209
1331
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.6
9.8
33
74
H02AB09
ATC
hydrocortisone; systemic
5.0
9.7
30
62
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
5.0
9.7
30
62
L04AA06
ATC
mycophenolic acid; systemic
6.5
9.6
24
38
L43.8
ICD-10 Finland
Other lichen planus
5.3
9.6
28
54
L28.1
ICD-10 Finland
Prurigo nodularis
8.5
9.6
20
24
SPAT1262
SPAT
Handing over of treatment supplies
1.8
9.5
171
1030
D07CC01
ATC
betamethasone and antibiotics; topical
2.1
9.5
108
546
XQ802
NOMESCO Finland
Epicutan test
3.9
9.4
38
102
L30.8
ICD-10 Finland
Other specified dermatitis
4.5
9.4
32
73
L51.19
ICD-10 Finland
Other bullous erythema multiforme
+∞
9.4
9
*
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
9.0
517
4273
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.8
8.9
184
1158
SPAT1254
SPAT
Administration of medicine
1.9
8.9
149
874
E000007
ATC
NA
2.9
8.8
51
181
SPAT1153
SPAT
Removal of sutures
1.6
8.8
268
1887
D07AA02
ATC
hydrocortisone; topical
2.1
8.7
108
564
A10BA02
ATC
metformin; oral
1.6
8.7
256
1782
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
8.7
244
1677
L43.1
ICD-10 Finland
Bullous lichen planus
50.5
8.7
10
*
E000002
ATC
NA
2.2
8.7
86
408
M05BA04
ATC
alendronic acid; oral
2.1
8.6
103
530
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.0
8.6
115
621
L10.2
ICD-10 Finland
Pemphigus foliaceus
+∞
8.3
8
*
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
5.6
8.3
23
42
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.7
8.3
182
1162
S17
ICPC
Abrasion/scratch/blister
4.2
8.2
30
74
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
8.1
159
979
XQ800
NOMESCO Finland
Prick test
2.8
8.1
51
191
L20.0
ICD-10 Finland
Besnier prurigo
3.1
8.0
43
146
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
7.9
226
1555
A07AA02
ATC
nystatin; oral
2.4
7.9
66
289
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.8
7.8
47
172
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.1
7.8
40
132
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
4.2
7.7
28
69
C08CA01
ATC
amlodipine; oral
1.5
7.7
321
2421
L89
ICD-10 Finland
Decubitus ulcer and pressure area
3.9
7.7
30
79
R53
ICD-10 Finland
Malaise and fatigue
1.7
7.7
181
1179
S02
ICPC
Pruritus
3.2
7.7
39
127
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.2
7.6
79
384
AA1AD
NOMESCO Finland
CT of head and brain
1.6
7.5
214
1464
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
7.4
156
981
N18.8
ICD-10 Finland
Other chronic renal failure
3.1
7.4
38
125
K13.78
ICD-10 Finland
Other change in the oral mucosa
4.4
7.4
25
58
L10.8
ICD-10 Finland
Other pemphigus
+∞
7.3
7
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
7.3
153
961
SPAT1263
SPAT
Sampling
1.5
7.3
323
2461
L43.9
ICD-10 Finland
Lichen planus, unspecified
4.3
7.2
25
60
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.1
7.1
76
377
R03AC02
ATC
salbutamol; inhalant
1.5
7.0
359
2815
A10BH02
ATC
vildagliptin; oral
3.6
6.9
29
82
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.2
6.9
68
326
E86
ICD-10 Finland
Volume depletion
3.1
6.8
35
116
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.3
6.8
57
253
E000006
ATC
NA
2.2
6.7
64
299
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
6.7
257
1886
A98
ICPC
Health maint/preventive medicine
1.7
6.6
693
6335
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.7
6.6
133
827
L50.9
ICD-10 Finland
Urticaria, unspecified
3.3
6.6
31
97
WX110
NOMESCO Finland
Local anesthesy
1.5
6.6
446
3693
SPAT1216
SPAT
Assessment of functional ability
1.7
6.5
151
975
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.9
6.5
25
66
WX892
NOMESCO Finland
Monitored bed care
2.2
6.5
67
324
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
6.5
245
1788
S21
ICPC
Skin texture symptom/complaint
1.9
6.5
104
597
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.5
6.5
49
205
K13.74
ICD-10 Finland
Lichen rubs planus in the mouth
6.3
6.5
16
26
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.2
6.5
31
98
C03AA03
ATC
hydrochlorothiazide; oral
1.9
6.5
97
547
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
6.5
124
758
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.5
6.4
235
1704
L01.0
ICD-10 Finland
Impetigo [any organism] [any site]
8.2
6.3
13
16
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
2.8
6.3
37
134
J01MA02
ATC
ciprofloxacin; systemic
1.5
6.3
311
2407
205
Kela drug reimbursment
Chronic hypertension
1.5
6.3
279
2110
RS311
NOMESCO Finland
NA
26.9
6.2
8
*
L28
ICPC
Limited function/disability (L)
1.6
6.2
154
1013
H02AB04
ATC
methylprednisolone; systemic
1.8
6.2
114
687
K12.00
ICD-10 Finland
Recurrent oral aphthae
5.8
6.2
16
28
M04AA01
ATC
allopurinol; systemic
1.7
6.1
124
768
R06.0
ICD-10 Finland
Dyspnoea
1.5
6.0
203
1442
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: L12_PEMPHIGOID – Pemphigoid
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).